5 May 2026

For Singapore researchers: A timely moment for impactful research


Singapore’s healthcare and research ecosystem is entering a pivotal phase. By 2030, one in four Singapore residents will be aged 65 or older. RIE2030 has committed S$37 billion to research and innovation, with its inaugural Grand Challenge — Maximising Healthy and Successful Longevity — targeting cognitive decline, physical function, and the biology of ageing. The National Precision Medicine programme has entered Phase III, Healthier SG is reshaping preventive care delivery, and novel therapeutic modalities are advancing through new regulatory pathways. The Annals invites high-quality submissions that translate these national investments into evidence for practice and policy.


Priority domains:

  • Healthy longevity and ageing — biological ageing, frailty, sarcopenia, dementia prevention, multimorbidity, healthspan extension
  • Precision medicine and genomics — pharmacogenomics, multi-ethnic Asian genomic epidemiology, biomarker-driven diagnostics, clinical implementation of genetic testing
  • Therapeutic innovation and regulatory science — novel biologics, cell and gene therapies, mRNA therapeutics, biosimilars, health technology assessment, real-world evidence
  • Cancer, cardiovascular, metabolic, and neurological diseases — Asian-specific epidemiology, risk stratification, treatment outcomes, survivorship
  • AI, data science, and digital health — clinical decision support, predictive analytics, real-world data, regulatory and ethical dimensions of health AI
  • Health services research and implementation science — Healthier SG evaluation, value-based care, care integration, health economics, quality improvement
  • Infectious diseases and pandemic preparedness — emerging infections, antimicrobial resistance, vaccines, surveillance systems
  • Population health, prevention, and health equity — community interventions, ethnic health disparities, health literacy, policy evaluation


What makes a submission competitive


Methodological rigour, relevance to Singapore’s or the region’s healthcare priorities, and explicit implications for practice or policy. We value work leveraging Singapore’s national cohorts, registries, and health data infrastructure. Submissions will be reviewed by our Editorial Board with decisions communicated promptly.


See Instructions for Authors before submitting your papers.